지난 강의 테마강의
Aging in health and aging-related diseases.
- 일시
- 2025.06.22(일요일) 09:00–17:00
- 회차 · 장소
노화는 단순한 시간의 흐름이 아닌, Cellular Stress Responses, Inflammation, Mitochondrial Dysfunction 등 복합적인 생물학적 기전의 결과입니다. 본 강의는 노화의 분자적 메커니즘을 이해하고, Healthy Aging을 위한 기능의학적 해법을 제시합니다.
"건강한 노화(Healthy Aging)를 위한 통합적 접근"
노화의 근본 원인(ATM)과 핵심 기전(Hallmarks of Aging)을 심층 분석하여, 유전적 요인뿐만 아니라 생활습관 및 환경적 요인이 노화에 미치는 영향을 알아봅니다.
치매, 파킨슨병 등 노인성 퇴행 질환의 조기 발견 및 예방을 위한 기능의학적 진단 검사(FM Labs)와 영양, 호르몬, 해독 등 맞춤형 치료 전략을 제시합니다.
기존 약물 치료의 한계를 넘어, 세포 노화를 억제하고 재생을 돕는 Senotherapeutics 및 최신 항노화 치료 트렌드를 소개합니다.
Aging & Functional Medicine은 100세 시대를 위한 필수 임상 지식입니다.
생물학적 노화를 늦추고 삶의 질을 높이는 체계적인 항노화 임상 솔루션을 확인해 보세요.
상세 커리큘럼
I. Introduction
- Biological age
- Primary aging
- Secondary aging
- Healthy aging and Role of Functional Medicine
II. Molecular mechanisms of aging
- Hallmarks of aging
- Biological theories of aging
- Cellular stress responses and aging stress responses
- Cellular Stress Responses: Hormesis against stress and disease
- Aging Stress Responses, Biology of Stress Responses in Aging
- Impaired nutrient signaling
- Oxidative stress response
- Maladaptive proteostatic response
- Genotoxic Stress: Maladaptive DNA damage response & Telomere attrition
- Cellular senescence
- Maladaptive mitochondrial stress response / mitochondrial quality control
- Inflammation and aging
III. Cellular stress responses in aging associated diseases
- CardioMetabolic diseases and aging
- Neurodegenerative disorders
- Immune inflammatory diseases and aging
- Cancer and aging
IV. ATM Causal factors of aging
- Nonmodifiable lifestyle factors
- Genetics and Epigenetics: Your Blueprint, Your Choices
- Age and sex
- Modifiable factors
- Life style factors
- External Environmental factors
- Pathogens: chronic infections
- Environmental factors
- Internal Environment: Mediators, Hallmarks of Aging
- Inflammaging and Oxidative Stress in aging
- Nutrient signaling, Nutrition and Longevity
- Hormonal Balance: the key to aging gracefully
- Gut Health: the foundation of longevity
- Metabolic imbalance & Detoxification imbalances
V. Evaluation to Support Healthy Aging
- Routine medical examination
- Functional Medicine Labs to Support Healthy Aging
- Comprehensive Functional Blood Testing for Optimal Health & Longevity
- Special Functional Medicine Labs(Nutritional Testing, Organic Acids, Gut Health Testing, Hormonal Balance, Detoxification Pathway Assessment, Methylation Panel, Genetic Testing)
- Tests for Biological Age
- Epigenetic clocks: DNA methylation
- Telomere length
- Markers in body fluids (inflammation, metabolic markers, hormone levels)
- Physiological tests (lung capacity, BP, vision, CV fitness)
- Cognitive tests
VI. Conventional Treatments for Aging
- Some typical conventional treatmentsDM, high BP medications, aspirin, and hormone replacement therapies
- Possible interventions and treatments against aging-related diseases
- Nondrug therapies: Exercise, dietary interventions, weight loss, CR, nutrition, Intestinal microbiota transplantation
- Drug therapies targeting aging mechanisms:
- Targeting Cellular Senescence (Senolytic, Senomorphic: Rapamycin, NAD+)
- Anti-inflammatory, antioxidant (Colchicine, biologic drugs, SGLT2 inhibitors)
- Nutrient sensing network & Metabolic intervention
- HRT
- Regenerative Therapies (stem cell, exosome, gene Tx)
VII. FM Approaches to Common Age-Related Health Conditions or for Healthy Aging
- Systems imbalance controlInflammation, Gut Health, Optimize nutrition, Cardiometabolic support, HRT, Detoxification
- Lifestyle modification
- Targeted Supplementation & HerbsAnti-inflammatories, Antioxidants, Caloric Restriction Mimetics, Mitochondrial Nutrient supplements, Senotherapeutics
- Complementary and Alternative Medicine
- New Frontiers of Science (Red light/near infrared light therapy, HBOT)
- Addressing Age-Related Health Conditions
VIII. Addressing Common Age-Related Health Conditions Pathological aging disorders
- Dementia and Alzheimer’s Disease
- Overview, Symptoms (Cognitive/Psychological), Types
- Possible Causes and Risk factors
- Stages and Complications (Clinical/Biological staging)
- Diagnostic evaluation: Medical Hx, Neurocognitive testing, Lab tests, Brain imaging (CT/MRI/PET), Psychiatric evaluation
- Conventional Medicine Tx: Pharmaceuticals, Non-Pharmacological Interventions
- FM approaches to AD: FM lab, FM Tx (Dietary/Lifestyle, Mediator control, Integrative programs, Supplements)
- Parkinson's Disease
- Introduction, Signs and symptoms
- ATM (Causes): Systemic imbalance (Gut/Gluten/Autoimmunity), Viral Infections, Lifestyle, Genetics
- Diagnosis: Physical/Neurological exam, Lab tests, Imaging (MRI/PET/SPECT/DAT), Alpha-synuclein test
- FM Treatment: Symptoms Management, Mediators control, Lifestyle, Botanicals/Supplements, Phototherapy, Mind-body therapies
- Age-related macular degeneration (AMD)
- Nocturia in the elderly
- Definition, Epidemiology, Sx, Impact on QoL
- Cause, Types, Voiding diary, Pathophysiology
- Clinical evaluation
- Management: Lifestyle modification, Behavioral therapy, Specific treatment, Pharmacological Therapy